Retinal degeneration in cats fed casein. III. Taurine deficiency and ERG amplitudes.

artery blood flow and the retinal oxygen tension, however, remained elevated for 15 min. Discussion. The VER from anesthetized animals has been extensively studied by others, and our recordings are similar to those they have obtained. It is not clear which cortical structures generate the different waves of the VER, but in the eye it appears to be primarily foveal in origin. We have previously shown that elevation of the intraocular pressure to levels similar to those used in this study decrease the optic nerve discharge. An increase in blood flow due to mannitol infusion should partially reverse the effects of elevation of the intraocular pressure on the visual evoked response if the effect of elevation of the intraocular pressure is on the intraocular vasculature. Thus the results of our study support the view that elevation of the intraocular pressure affects intraocular blood flow. The effect of mannitol infusion on axoplasmic flow in the optic nerve is not •known.